The interplay of chronic pathogens with the immune system
The innate and acquired mechanisms of the immune system play central roles in the control of chronic infections. Many pathogens have developed their own mechanisms by which they can evade components of the immune system. Important aspects of this interplay between pathogen and host during the establishment of a chronic infection are being investigated in the section B projects. Particular emphasis is placed on persistent herpesviruses.
The infection research with regard to immunological aspects on viral and bacterial pathogens can display common features of these different agents.
Projects in project area B
B1 – Förster / Messerle
Visualization of herpes virus infections and immune response as well as their modulation
B3 – Melanie Brinkmann
Modulation of the innate immune response by the gammaherpesviruses Kaposi´s sarcoma-associated herpesvirus and murine herpesvirus 68
B3 – Stephan Halle
Modulation of the innate immune response by the gammaherpesviruses Kaposi´s sarcoma-associated herpesvirus and murine herpesvirus 68
B8 – Prinz / Könecke
Towards the use of antigen-specific γδ T lymphocytes for CMV virus control after allogeneic stem cell transplantation
B9 – Abel Viejo Borbolla
Immune modulation and colonization of sensory ganglia by alphaherpesviruses
B10 – Thomas Krey
Structural flexibility in the Hepatitis C virus glycoprotein complex as viral strategy to evade the humoral immune system
B11 – Sarina Ravens
The interplay of EBV-induced γδ and αβ T cells during chronic EBV reactivation, PTLD, and EBV-directed cellular therapy in transplant recipients
B11 – Britta Maecker-Kolhoff
The interplay of EBV-induced γδ and αβ T cells during chronic EBV reactivation, PTLD, and EBV-directed cellular therapy in transplant recipients
